Frank suffers as he went through detox from DL56. Karen gives him half the regular dosage of the drug under pressure from Joe and Julie. He's a ticking time bomb with this stuff, Karen says. She and Joe fight about the best course of treatment for Frank. Inside Frank's room, Frank asks Julie not to say anything to Mary about the drug. She wants to, but agrees to keep up their story that he got addicted to pain killers after the accident. He apologizes to her for being so cruel. They share a kiss.

Garcia talks to Chris about Frank. When Chris asks Julie what is going on, she starts to give him their story about pain killers, but Chris told her that he already knows, thanks to Garcia. Later, Chris calls his contact at Lance Pharmaceuticals and offers information on a human test case of DL56.

Garcia confronts Karen about giving Frank DL56--she denies it. He confronts Frank, trying to get him to confess, but Frank just laughs at him.

The surgeon who performed Serena's surgery is optimistic that the transplant was successful. Eve and Scott hug when they hear the news, while Lucy glares at them from the corner. Later, as Scott visits with Serena, she told him how much she is looking forward to being able to see again so she can look for Dominique's star. Lucy joins them. Serena asks about wedding plans and about Eve. When Lucy hesitates to answer about Eve, Serena told Lucy and Kevin that it was just an accident and not Eve's fault for what happened to her. She asks Lucy if she could get Eve to visit her more often. Lucy, in tears, asks Eve grudgingly to visit Serena--because it's what she wants, not what I think is a good idea, she says. During their visit, Serena told Eve not to be sad about the car crash. The surgeon arrives and wants to take Serena's bandages off. Slowly he removes them, but it's no use. Serena still can't see.

The surgeon told Scott that if Serena's immune system rejects the steroids that he's going to use to help bring the swelling down with, she could become permanently blind. Scott freaks out, and Karen tries to comfort him. He questions his parenting skills to Lucy, who told him that he's a great father and that he can't be with Serena 24 hours a day. Inside, Scott and Serena discuss her condition. He convinces her to be patient and that there is no reason to give up hope.

Lucy runs into Eve and asks who she's planning to kill next, now that Dr. May's corneas aren't working. You, Eve says. Eve takes Scott some clothes and a toothbrush. I called Gail to watch Serena while you freshen up, she says. I know you wouldn't leave her alone with me. Serena asks Eve to read to her, but before she begins, Lucy burst in with Serena's flower girl dress. Eve leaves. Serena asks if she can still be in the wedding even though she can't see. Of course, Lucy says. Just then, the phone rings. Lucy learns that the roof has collapsed in the church and they have to postpone the wedding for a week while it's repaired. She asks Serena to help her make calls to let everyone know.

Julie visits Frank after her shift is over. They start kissing and wind up throwing their clothes on the bed as they head for the bathroom. They make love in the shower while outside, an orderly comes in to make up Frank's bed. He accidentally takes all their clothes with him. They come outside and realize what happened. Frank has Karen paged to his room and asks her for two pairs of scrubs. What for? Karen wants to know. Julie comes out in a towel and explains what happened. Karen teases them, but agrees to help out.

Karen told Kevin that Dr. May's husband mentioned that she had a congenital heart condition, so she may not have been poisoned--but they will have to wait for the autopsy report. At home, Kevin gets caught in a trap that Victor has set. Victor is ecstatic--his plan works! Kevin asks how he plans to get the killer to come to the house. With a carrot, Victor replies. I'm going to figure out the next victim. Kevin starts telling him how ridiculous and dangerous this is when he gets a call from Mac. The autopsy report is in...Dr. May was poisoned with cyanide, just like in General Homicide.

Karen reminds an agitated Frank that they'll have to cut his dosage in half once again to make certain the detox process continues. Determined to get his hands on more of the DL-56, Frank decides to appeal to Lark. Karen warns Julie that all of the test animals she's weaned off the DL-56 maintained the same behavior they displayed while they were on the drug. Later, Lark promises Karen she won't help Frank score a new supply of DL-56. Frustrated to see an opportunity for big bucks slipping away fast, Chris told the people at Lance Pharmaceuticals that he's conducting a human test of the new drug that has proved wildly successful. Enraged when Lark refuses to assist him, Frank accuses the girl of betrayal and orders her to get out. As Garcia begins working on a new theory for his investigation, Julie and Karen shakily admit to one another their fear that Frank could be the serial killer. Frank vows to blackmail Karen unless she provides him with higher doses of the drug she created. Undaunted by a junkie's threats, Karen calmly calls her patient's bluff. Afterwards, Chris offers to supply Frank with all the DL-56 he wants if he'll play human guinea pig.

Joe is dismayed to hear how his brother tried to blackmail Karen. Meanwhile, in the detox ward, Chris injects Frank with a full dose of DL-56. Garcia comes to the lighthouse to question Kevin, who bristles at the suggestion that he killed Dr. May in order to boost flagging sales of his book. Though Victor leaps to his son's defense, Garcia reminds both Dr. Collins that Kevin is still very much a suspect. Serena's ballet teacher and her classmates send a special gift to the hospital to cheer up their young friend. Later, worried that Michelle will say something about her unscheduled appearance at the dance studio on the day of the accident, Lucy asks the teacher not to visit Serena for a while. Kevin speculates about why he has become the focus of the real serial killer's hatred. Panicked to learn that Joe intends to draw more blood for tests, Frank calls on Chris to throw the lab boys a curve. Eve overrules Lucy and ushers Michelle into Serena's room for a visit. Kevin decides to use himself as bait for the murderer. Joe persuades Karen to release Frank after his latest round of tests come back clean.